Research Profiles: LC-ESI-MS/MS draws the line on doping

Matrix effect in LC-ESI-MS and LC-APCI-MS with off-line and on-line extraction procedures.

Matrix effect on mass spectrometry response was investigated with commercially available electrospray ionisation (ESI) and atmospheric pressure chemical ionisation (APCI) sources coupled with a single quadruple mass spectrometer. A post-column infusion system was used to observe the MS signal alterations of methadone, selected as the model compound, in plasma. For this purpose, two sample prepa...

on the status of mixed methods research in applied linguistics

چکیده ندارد.

Coupling LC with On - line ESI and Off - line MALDI – MS / MS for Maximum Information Readout from Protein Samples

were re-crystallized with ethanol/acetone/0.1%TFA (60:30:10, v:v). MS and MS/MS spectra were obtained fully automatically on an ultraflex MALDI–TOF/TOF mass spectrometer (Bruker Daltonics). The WARP–LCTM software controlled the intelligent precursor ion selection and BioTools 3.0 was used for ESI and MALDI spectra validation (both Bruker Daltonics). Database search: Mascot Version 2.0.05 (www. ...

Criminalization of medical error: who draws the line?

As stakeholders struggle to reconcile calls for accountability and pressures for increased patient safety, criminal prosecution of surgeons and other health-care workers for medical error seems to be on the rise. This paper examines whether legal systems can meaningfully draw a line between acceptable performance and negligence. By questioning essentialist assumptions behind 'crime' or 'neglige...

Research Investigation of Laser Line Profiles